Effect of deep TMS on resting state functional connectivity of Default Mode Network and its clinical correlates in schizophrenia patients with prominent negative symptoms - SOCODM

IndiaAlliance,DBT wellcome0 个研究点目标入组 0 人开始时间: 待定最近更新: 2023年4月3日

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•1 Patients with diagnosis of schizophrenia as per DMS 5 and prominent negative symptoms with a score of 3 or more on each domain of affective flattening, alogia, avolition-apathy and anhedonia-asociality in Scale for Assessment of Negative Symptoms (SANS)
•2 Stable dose of oral antipsychotics (defined as <25% change in dose) for the past 6 weeks and/or parenteral antipsychotics for the past 12 weeks
•3 Age of 18 â?? 60 years
•4 Both male and female gender
•5 Written informed consent from the patient

•1 Psychiatric emergency necessitating parenteral rescue medications or electroconvulsive therapy
•2 Pregnancy or postpartum state
•3 Substance use disorder in last 6 months
•4 Co-morbid neurological or medical disease that can affect the brain structure or function
•5 Any contraindication for Magnetic Resonance Imaging
•6 Any contraindication for Transcranial Magnetic Stimulation
•7 Clinically determined visual or hearing impairment

发起方

IndiaAlliance,DBT wellcome