Improving surgical treatment outcomes in Hip Osteoarthritis based on Biomechanical and Biomarker Discoveries
Recruiting
- Conditions
- M16.9Coxarthrosis, unspecified
- Registration Number
- DRKS00024732
- Lead Sponsor
- Klinik für Orthopädie (Friedrichsheim), Universitätsklinikum Frankfurt
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
Indication and performance of a total hip replacement surgery.
Free standing and walking without support of aids
Exclusion Criteria
BMI = 35;
Previous arthroplasty of the hip, knee, or ankle joint;
Osteoarthritis in the ipsilateral/contralateral knee joint (Kellgren Lawrence scale >2);
Surgical procedures on the musculoskeletal system in the past 6 months;
Prior joint infections or destructive rheumatoid arthritis;
Neurologic disease (e.g., Parkinson's disease, stroke with paralysis component, muscular dystrophy, epilepsy, multiple sclerosis, paraneoplastic neurologic syndrome (PNS), tremor, Alzheimer's disease, chorea, Huntington's disease, polio, cerebral palsy);
Lower extremity injuries;
Failed consent
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The identification of patients before surgery who are likely to have an increased risk for developing OA in other joints based on biomechanical gait parameters and / or biomarkers from blood and synovial fluid.
- Secondary Outcome Measures
Name Time Method Impact of the leg alignment in general and specifically the restoration of the offset and leg length on the development of the abductor force and consequently the development of a healthy gait pattern for all joints