Does Cold Provocation Increase Brown Adipose Tissue Volume?

Not Applicable

Completed

• Conditions: Brown Adipose Tissue, Human

• Registration Number: NCT01797328
• Lead Sponsor: University Hospital, Linkoeping

Brief Summary

About 28 healthy subjects are randomized to 1 hour/day of coldprovocation or to the best of ability to avoid feeling cold, for 6 weeks. Basal metabolic rate and magnetic resonance (for determination of brown adipose tissue volume) imaging are performed before and after the study.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-02
• Study First Submitted: 2013-02-18
• Study First Submitted QC: 2013-02-20
• Study First Posted: 2013-02-22
• Primary Completion: 2015-05
• Study Completion: 2015-06
• Results First Submitted: 2016-10-26
• Status Verified: 2017-04
• Results First Submitted QC: 2017-04-24
• Last Update Submitted: 2017-04-24
• Results First Posted: 2017-04-25
• Last Update Posted: 2017-04-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 28

Inclusion Criteria

healthy subjects -

Exclusion Criteria

any significant disease, ot other conditions that interferes with magnetic resonance imaging

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Brown Adipose Tissue, Absolute Volume	Baseline and 6 week	Sub-clavicular brown adipose tissue volume by magnetic resonance imaging (liters)

Trial Locations

Locations (1)

Faculty of Health Science, Linköping; 🇸🇪 Linköping, Sweden