Clinical Characteristics of Pruritus and Evaluation of Quality of Life in Patients With Bullous Pemphigoid

Completed

• Conditions: Bullous Pemphigoid

• Registration Number: NCT03272958
• Lead Sponsor: University Hospital, Brest

Brief Summary

Whereas pruritus is a major symptom in bullous pemphigoid, its characteristics and its impact on quality of life have been little studied.

The objective of this study is to learn more about pruritus characteristics of patients with bullous pemphigoid, and in consequence to better understand the pathophysiology of pruritus, and then to better treat pruritus in this condition.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-07-21
• Study First Submitted QC: 2017-09-03
• Study First Posted: 2017-09-06
• Study Start: 2017-11-07
• Primary Completion: 2018-10-03
• Study Completion: 2018-10-03
• Status Verified: 2019-01
• Last Update Submitted: 2019-01-04
• Last Update Posted: 2019-01-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 63

Inclusion Criteria

• adult
• pruriginous bullous pemphigoid lately diagnosed.
• Without PB treatment
• MMS (Mini Mental State Examination) ≥ 21
• In hospitalization or consultation

Exclusion Criteria

• pregnant woman
• nursing women

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Clinical characteristics of pruritus in patients with bullous pemphigoid	Day1 ( when diagnosis of bullous pemphigoid is made)	Answers and scores in questionnaire about clinical characteristics of pruritus Demographics characteristics of patients Characteristics of the bullous pemphigoid

Secondary Outcome Measures

Name	Time	Method
Impact of pruritus on quality of life in patients with bullous pemphigoid	Day 1 (when diagnosis of bullous pemphigoid is made )	score ABQOL

Trial Locations

Locations (16)

CHRU de Brest; 🇫🇷 Brest, France

CH Argenteuil; 🇫🇷 Argenteuil, France

HP-HM; 🇫🇷 Marseille, France

CH de Niort; 🇫🇷 Niort, France

AP-HP, Hôpital Avicenne; 🇫🇷 Bobigny, France

CHU Le Havre; 🇫🇷 Le Havre, France

CHU de Bordeaux; 🇫🇷 Bordeaux, France

CHU Caen; 🇫🇷 Caen, France

CHU de Rouen; 🇫🇷 Rouen, France

CHU de Clermont-Ferrand; 🇫🇷 Clermont-Ferrand, France

CHU de Reims; 🇫🇷 Reims, France

AP-HP, Hôpital Bichat; 🇫🇷 Paris, France

CHU de Montpellier; 🇫🇷 Montpellier, France

CHU de Saint-Etienne; 🇫🇷 Saint-Étienne, France

AP-HP, Hôpital Henri Mondor; 🇫🇷 Créteil, France

AP-HP, Hôpital Cochin; 🇫🇷 Paris, France