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Clinical Trials/NCT04985591
NCT04985591CompletedEarly Phase 1

The Effect of Liposuction on Menses: a Retrospective Study

Shanghai Jiao Tong University School of Medicine0 sites516 target enrollmentStarted: June 14, 2016Last updated:
Conditions

Trial Snapshot

Phase
Early Phase 1
Status
Completed
Sponsor
Enrollment
516
Primary Endpoint
menstrual irregularity

Study Overview

Brief Summary

The prevalence of obesity nearly tripled from 1975 to 2021, resulting in liposuction, as an effective shaping method, to be performed more frequently. Liposuction is a surgical procedure that uses a specialized instrument to suck fat fragments in the subcutaneous fat layer through a small incision. Analyzing a large sample sizes of patients who had liposuction, we found that some female patients underwent menstrual irregularity after liposuction. In 2004, Carolyn et al. reported several cases in which there was a connection between liposuction and an early onset of menses. Further studies showed that an early onset of menses may be related to the volume of adipose tissue extracted, the amount of anesthesia given, the area of liposuction, and body weight. However, the sample of that study was small, as there were only 17 cases included in the statistical model, and there are few articles in which the impact of liposuction on menses has been studied. To better understand whether menstrual irregularity will occur after liposuction, patients with postmenopausal or preoperative menstrual irregularity were excluded, leaving a sample of 518 female patients to be reviewed. A better understanding of the impact of liposuction on menses may help clinical doctors predict the underlying risk of menstrual irregularity after liposuction and identify individuals at higher risk. The findings may contribute to further understanding of menstrual irregularity.

Study Design

Study Type
Interventional
Allocation
Non Randomized
Intervention Model
Parallel
Primary Purpose
Prevention
Masking
None

Eligibility Criteria

Ages
18 Years to 55 Years (Adult)
Sex
Female
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • patients who were in 18-55 and have a regular menses -

Exclusion Criteria

  • Patients who were younger than 18 years old or older than 55 years old, who were in the perimenopausal or postmenopausal stage or who had menstrual irregularity before plastic surgery were excluded from both groups.

Outcomes

Primary Outcomes

menstrual irregularity

Time Frame: three months

to detect any change in the menses during the following 3 months, post surgery

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
Shanghai Jiao Tong University School of Medicine
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Qing-FengLi Li,MD

Professor

Shanghai Jiao Tong University School of Medicine

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