Effect of gluten free diet in treatment of IBS

Not Applicable

• Conditions: Irritable Bowel Syndrom.; Other diseases of intestines; k55-k64

• Registration Number: IRCT20100524004010N26
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 14 January 2019

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

18-65 years
Patients with irritable bowel syndrome, according to gastroenterologist diagnosed according to the ROME- IV criteria (1.Improvement with defecation 2.Onset associated with a change in stool frequency 3.Onset associated with a change in stool form (appearance) At least three days a month, three months a year and no pathological findings in the clinical investigating)
lack of any organic intestinal disease(diagnosed by last 5 years ago colonoscopy) and intestinal infections(diagnosed by stool culture).
No medical history of chronic gastrointestinal and colorectal disease
Absence of any major bowel surgery
Absence of regular use of laxatives or antidiarrheal drugs
No chronic use of antibiotics, corticosteroids and immunosuppressants
No usage of drugs that modifying the digestive motility such as metoclopramide, cisapride, diphenoxylate,…
No usage of drugs that increased bleeding of intestinal mucosa such as aspirin, warfarin, heparin,…
No history of breast cancer in patient or in first-degree relatives of a person
Absence of severe mental or behavioral disorder
Absence of nicotine and its derivatives use in last 6 months
No usage of NSAIDs and aspirin in last week(influence on gut permeability)

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Age. Timepoint: Beginning of study. Method of measurement: Question.;Gender. Timepoint: Beginning of study. Method of measurement: Observation.;Weight. Timepoint: Beginning and end of study. Method of measurement: Balance.;Height. Timepoint: Beginning and end of study. Method of measurement: Meter.;BMI. Timepoint: Beginning and end of study. Method of measurement: Calculation.