Different Techniques for Lung Ventilation During Cardiac Surgeries
Not Applicable
Recruiting
- Conditions
- Coronary artery disease, valvular disease.I20.0I05.9
- Registration Number
- RBR-38fknk
- Lead Sponsor
- niversidade Estadual de Campinas
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- Not specified
Inclusion Criteria
Age between 19 and 90 years. Ambos sexes. Cirurgia elective coronary artery bypass grafting with or without associated procedures. Surgery of exchange and valvuloplasty. Cirurgia of aneurysms of the ascending aorta and aortic arch. Pacientes who agreed to participate in the study by signing the consent form.
Exclusion Criteria
Age less than 19 years or greater than 91 years. Urgent surgery.
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Expect to see that maintaining a positive pressure during CPB and recruitment maneuver after CPB improves blood oxygenation levels compared to the control group in the immediate postoperative cardiac surgery.<br>The variables that analyze gas exchange will be obtained by arterial blood gas sample in 5 stages: pre extra corporeal circulation (before the patient enters into CPB), after extra corporeal circulation (after sternum closure), admission to the unit intensive, 1st postoperative (24 hours after surgery) and 2nd postoperative (48 hours after surgery).;Expect with the recruitment maneuver decrease the duration of mechanical ventilation in the immediate postoperative period, decreasing pulmonary complications and shorter ICU stay, compared to control patients who underwent no intervention ventilation.<br>For analysis of these outcomes, we use an evaluation form that will be annotated data restistência compliance and lung, as well as the time of ICU admission, time of extubation and mechanical ventilation.
- Secondary Outcome Measures
Name Time Method Expect with recruitment maneuvers decrease the incidence of systemic inflammatory response in the immediate postoperative cardiac surgery and thus reduce pulmonary complications,compared to control patients who underwent no intervention ventilation.<br>These variables will be assessed by inflammatory cytokine interleukin-1 among them, Interleukin-6, Interleukin-10 and Interferon-Gamma