Follow up MISSION!: Optimization of chronic care for patients with acute myocardial infarction and long term course of cholesterol.

Conditions: Atherosclerosis
stenosis
10011082
10003216

Registration Number: NL-OMON43755

Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: Not specified

Target Recruitment: 600

Inclusion Criteria

- All consecutive patients with ST-elevated myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI) treated by the MISSION! Protocol from 01-02-2004 to 31-12-2013.
* STEMI is defined as ongoing chest pain (>30 minutes), accompanied with ST-elevation (*0.2
mV in *2 leads in V1-V3 or *0.1 mV in other leads) or presumed new left bundle branch block (LBBB) and a typical rise and fall of cardiac biomarkers. Patients with a cardiac arrest are only analyzed if there is return of spontaneous circulation at the time of treatment in the catheterization lab.;- Place of residency area Hollands-Midden Noord at the time of index infarction.;- Measured lipid spectrum (Total-cholesterol, LDL-cholesterol, HDL-cholesterol and triglycerides) at the time of index infarction.

Exclusion Criteria

- Patients with other acute coronary syndromes as non-ST-elevated myocardial infarction or unstable angina pectoris, not treated with primary PCI are excluded. Patients will also be excluded in case of cardiac arrest without return of spontaneous circulation at the time of primary PCI.;- If the permanent residence of the patient is not in the Netherlands, follow-up for clinical outcomes can be difficult. For this reason these patients will be eliminated for clinical outcome analysis.;- Not completed outpatient follow up according to the MISSION! guidelines, up to one year following index infarction.

Study & Design

Study Type: Observational invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>- Association between baseline characteristics, place of referral and<br /><br>poorly controlled lipid levels. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- A major coronary event after one year follow up (defined as death from CHD,<br /><br>nonfatal non*procedure-related myocardial infarction, or resuscitation after<br /><br>cardiac arrest), a cerebrovascular event, hospitalization for congestive heart<br /><br>failure, peripheral-artery disease, death from any cause, any cardiovascular<br /><br>event, and any coronary event.<br /><br><br /><br>- Statin compliance using the MMAS (Morisky Medical Adherence Scale). </p><br>