A multicentre randomized control study of atrial fibrillation in heart failure (CAMERA-MRI)

Not Applicable

Completed

• Conditions: Atrial Fibrillation; Heart Failure; Cardiovascular - Other cardiovascular diseases

• Registration Number: ACTRN12613000880741
• Lead Sponsor: Baker IDI Heart & Diabetes Institute

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-08-07
• Study Completion: 2017-05-08
• Last Update Posted: 17 February 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 66

Inclusion Criteria

Paroxysmal or persistent AF
LVEF < 45%
Dilated Cadriomyopathy

Exclusion Criteria

Non MRI safe Pacemaker, ICD or BiVentricular Device
Renal Impairment Cr > 200
Left atrial thrombus

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Recovery of Left Ventricular function assesed by improvement in Ejection Fraction determined by cardiac MRI and Echocardiography.[Assessed at 6 months.];Restoration of sinus rhythm assessed by Loop Recorder Interrogation (Catheter Ablation Arm) Holter Monitoring and Electrocardiography (Rate Control Arm).[Loop Recorder assessed at 6 weeks, 3 and 6 months.<br>Holter Monitoring assessed at 3 and 6 months.]

Secondary Outcome Measures

Name	Time	Method
Improvement in Heart Failure symptoms as assessed by the 6 Minute Walk Test (6MWT) and Quality of Life as assesed by the individual participant using the SF36v2 Health Survey.[6MWT and SF36 assessed at 3 and 6 months. <br>]