Trombocytopathy in the Netherlands
Recruiting
- Conditions
- Platelet function disorders Trombocytopathie
- Registration Number
- NL-OMON22771
- Lead Sponsor
- MC Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 150
Inclusion Criteria
Age > 18 years
- History of bleeding diathesis suspected for a PFD
Exclusion Criteria
- Inability to give informed consent
- Bleeding diathesis due to an acquired PFD, von Willebrand disease, hemophilia or other disorders of secondary hemostasis or fibrinolysis
Study & Design
- Study Type
- Not specified
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method - Frequency and severity of bleeding symptoms: bleeding score using the ISTH-BAT <br /><br>- Treatment of bleeding diathesis: type and frequency of treatment received in the past (local treatment, antifibrinolytics, DDAVP, platelet transfusion) <br /><br>- Impact of PFD on quality of life: RAND-36 health survey score
- Secondary Outcome Measures
Name Time Method - Diagnostic utility of additional platelet tests as compared to standard LTA <br /><br>- Relation between type of PFD and bleeding phenotype <br /><br>- Genotype-phenotype relationship