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Probiotic yogurt consumption on weight loss

Phase 2
Conditions
Obesity.
Obesity due to excess calories
Registration Number
IRCT201402177754N8
Lead Sponsor
ovin Diet Clinic
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
Female
Target Recruitment
80
Inclusion Criteria

Willingness to enrollment to the study;Waist circumference > 88 cm;Non smoking; No-menopause;BMI: 25-45 kg/m2;Good general health;Normal lipid level (healthy obese);No- diabetes;Able to give informed consent and report side effects;
Exclusion criteria:Antibiotic treatment;Drugs that control glucose or lipid profiles;
Pregnancy or have given birth in the past year or planning pregnancy in the next 6 months;Lactation;Menopause women;Cancer or chemo/radio therapy;Chronic disease;Competitive athletes;Consumption of probiotic products;History of alcohol use;Abnormal thyroid hormone level;PCOD women;Intake of medications that could affect body weight and/or energy expenditure;Family history of T2DM in first degree relatives Allergy to probiotic or dairy products;Anemia;Recent history of large weight fluctuations;Immune compromised conditions;
Current use of antihypertensive medications; depression;
Prediabetes; Smoking; CVD; Active colitis; Solid organ transplant; Fatty liver

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Body weight. Timepoint: 0 and 12 weeks. Method of measurement: balance.
Secondary Outcome Measures
NameTimeMethod
Waist circumference. Timepoint: 0 and 12 weeks. Method of measurement: meter.;Fasting insulin level. Timepoint: 0 and 12 weeks. Method of measurement: ELISA kit.;Insulin resistance. Timepoint: 0 and 12 weeks. Method of measurement: HOMA-IR.;Hs-CRP. Timepoint: 0 and 12 weeks. Method of measurement: ELISA.;Lipid profiles. Timepoint: 0 and 12 weeks. Method of measurement: autoanalyzer.;Liver function tests. Timepoint: 0 and 12 weeks. Method of measurement: Autoanalyzer.
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