Comparison of serum ferritin level guided and standard practice of oral iron supplementation in very preterm neonates
Not Applicable
- Conditions
- Health Condition 1: P073- Preterm [premature] newborn [other]
- Registration Number
- CTRI/2024/05/066651
- Lead Sponsor
- Rainbow Children s Hospital and Birthright .
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Neonates less than 32 weeks of gestational age hospitalized in NIC
Exclusion Criteria
Preterm neonates whom iron supplementation is deferred because as in
1.Those with an active, culture-proven infection, or positive sepsis screen
2.A major surgical malformation of gut
3.Neonates in whom bowel resection is done
4.Neonates with Stage II and III Necrotizing enterocolitis
5.Cyanotic congenital heart disease
6.Neonates with hemoglobinopathies.
7.Neonates diagnosed with inflammatory conditions like hemophagocytic lymphohistiosis (HLH).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Determining the optimal age (in day of life) for initiation of oral iron supplementation at the time of full feed achievement and at 2 weeks of life (whichever is later) by serum ferritin monitoring compared with the standard practice.Timepoint: 2 weeks to 4 weeks
- Secondary Outcome Measures
Name Time Method 1.Total quantum (in mg) of oral iron supplemented during the NICU stay. <br/ ><br>2.Number of LRBC transfusions administered during their stay in NICU. <br/ ><br>3.Mean serum ferritin levels at the time of discharge in both groups. <br/ ><br>Timepoint: At discharge (8-10 weeks)