Prognostic Value of Combined Central Venous Oxygen Saturation and Lactate in Pediatrics Following Cardiac Surgery.

Not Applicable

• Conditions: Circulatory System; Paediatrics; Cardiology

• Registration Number: PACTR202104905893217
• Lead Sponsor: Facullty of medicine Menofia University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-04-10
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

On-pump & off-pump cardiac operation.
The presence of a central venous catheter in the internal jugular position available after surgery.

Exclusion Criteria

- Intraoperative cardiac arrest
- Massive perioperative bleeding
- Presence of a PA catheter
- Use of extracorporeal membrane oxygenation (ECMO) on ICU arrival
- Presence of a ventricular assist device (VAD)
- Pre-existing congestive cardiac failure, cardiomyopathy, hemodynamic instability, arrest or need of inotropic support before the operation
- Elevation of any parameters preoperatively indicating systemic hypoperfusion, coagulopathy, renal failure (serum creatinine >2 mg/dl, anuria, or oliguria requiring dialysis), hepatic dysfunction (aspartate aminotransferase >40 U/L, alanine aminotransferase >40 U/L) immediately before surgery
- Local or systemic infection or inflammation (fever, leukocytosis, tachycardia, or tachypnea, white blood cell count >12,000 cells/mm3, or platelet count <100,000 cells/mm3) immediately before surgery
- Reoperation

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
In-hospital mortality.<br>;Major complications (infection, sepsis, stroke, pulmonary embolism, prolonged mechanical ventilation, and renal failure)<br>

Secondary Outcome Measures

Name	Time	Method
ICU length of stay LOS<br>