Clinical trial evaluation the effect of melatonin on analgesia and intraocular pressure in patient with cataract surgery under topical anesthesia.
Phase 2
- Conditions
- cataract.Senile incipient cataract
- Registration Number
- IRCT20160430027677N8
- Lead Sponsor
- Oroumia University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
Patients aged 50–80 years
Patients with American Society of Anesthesiologists (ASA) physical status classification I–III
Elective cataract surgery with intraocular lens implantation using phacoemulsification for the first time
Surgery under topical anesthesia
Exclusion Criteria
Patients with sleep disorders; ;; ;;;; ; ; ; .
Autoimmune disease
Diabetes
Depressive disorder
Epilepsy
Deafness
Nystagmus
Allergy to the study drugs
Those who could not tolerate Shioetz tonometer during IOP measurement
Ongoing treatment with opioids
Analgesic treatment
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain. Timepoint: Pain scores were will be measured and recorded 60 minutes before receiving premedication (T1) after receiving premedication during admission to the operating room (T2), during surgery (T3) and after the surgery, before being discharged from the recovery room (T4). Method of measurement: Verbal Pain Score.;Anxiety. Timepoint: Anxiety scores were will be measured and recorded 60 minutes before receiving premedication (T1) after receiving premedication during admission to the operating room (T2), during surgery (T3) and after the surgery, before being discharged from the recovery room (T4). Method of measurement: verbal anxiety score.
- Secondary Outcome Measures
Name Time Method Intraocular pressure. Timepoint: Intraocular pressure was only will be measured and recorded before premedication and after surgery in the recovery room. Method of measurement: Schiotz tonometer.