H release by the pituitary, the inhibitive effect of circulating estradiol in obese and non-obese me

• Conditions: obesity; 10014701

• Registration Number: NL-OMON31039
• Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

male, BMI > 35 kg/m2, age < 40 years

Exclusion Criteria

history of hypogonadism, pituitary disease, venous thrombosis. Use of testosterone, aldactone, finasteride, glucocorticoids. LH > 8 IU/L

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>before every change of estradiol dose and at the end of the study blood is<br /><br>drawn for determination of estradiol, testosterone, sex hormone binding<br /><br>globulin and LH</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>non applicable</p><br>