The Effect of Nasal Hair on Nasal Obstruction

Not Applicable

Completed

• Conditions: Nasal Obstruction
• Interventions: Procedure: Vibrissae trimming; Drug: Application of oxymetazoline

• Registration Number: NCT01850511
• Lead Sponsor: Mayo Clinic

Brief Summary

Nasal obstruction is a common complaint prompting presentation to an otolaryngologist. Many studies have been performed quantifying and describing the impact of a number of factors on symptoms of nasal obstruction, including anatomical, neoplastic, infectious, and inflammatory causes. Despite this scrutiny, no attention has been paid to the nasal vibrissae as a potential anatomical contributor to nasal obstruction. The proposed study intends to elucidate that contribution, if any exists.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-05
• Study First Submitted: 2013-05-03
• Study First Submitted QC: 2013-05-07
• Study First Posted: 2013-05-09
• Primary Completion: 2013-10
• Study Completion: 2013-10
• Status Verified: 2019-04
• Last Update Submitted: 2019-04-19
• Last Update Posted: 2019-04-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Presence of nasal vibrissae
• Able to tolerate rhinomanometry

Exclusion Criteria

• Anatomical or other obvious cause of obstruction
• Claustrophobia with rhinomanometry mask

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Vibrissae trimming	Vibrissae trimming	Patients will serve as their own control, with assessment of primary outcomes pre- and post-trimming of vibrissae.
Vibrissae trimming	Application of oxymetazoline	Patients will serve as their own control, with assessment of primary outcomes pre- and post-trimming of vibrissae.

Primary Outcome Measures

Name	Time	Method
Nasal airflow/pressure	Participants will undergo assessment over a 30 minute period, no follow-up	Objective measures include airflow and pressure as assessed by Rhinomanometry.
Subjective Nasal Obstruction	Participants will undergo assessment over a 30 minute period, no follow-up	Subjective measures will be assessed via the modified version of the NOSE outcome instrument-a validated test of subjective nasal obstruction

Trial Locations

Locations (1)

Mayo Clinic in Rochester; 🇺🇸 Rochester, Minnesota, United States