assessment of bone healing after endodontic surgery using two bioresorbable membranes
- Conditions
- Medical and Surgical,
- Registration Number
- CTRI/2020/12/029599
- Lead Sponsor
- Department of Conservative Dentistry and Endodontics
- Brief Summary
Theprimary goal of endodontic surgery is to eliminate periradicular pathology andaid regeneration of the periapical tissues including the complete healing ofosseous defects. Apico-marginaldefects are localized bony defects that include the entire length of the rooti.e., defect which extends from the periapex tothe alveolar crest to the tooth. This defect caused by combinedperiodontal-endodontic lesion or an endodontic-periodontal lesion. Thetreatment of endodontic-periodontal combined lesions requires both endodontictherapy and periodontal regenerative procedure. Advancement in newer guidedtissue regeneration technique and development of second-generation plateletconcentrate, platelet rich fibrin shows promising result in field of endodonticsurgery. PRF promotes healing of wound, flap stabilization, osseous growth andhemostasis. The present study assess the one-year postoperative healingoutcome of Apico-marginal bone defects treated by endodonticmicrosurgery using two guided regenerative technique. The GTRtechnique compared included placement of a collagen membrane with and withoutthe adjunctive utilization of PRF over the apico-marginal and osseous defectbefore flap closure after performing endodontic microsurgery.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 30
negative response to vitality tests with radiographic evidence of periapical radiolucencies.
pathology amenable to healing by NSRCT, clinical or radiographic evidence of vertical root fracture, teeth with an earlier history of endodontic surgery, uncooperative patient or patient with a compromised medical history for an oral surgical intervention including uncontrolled diabetes and tuberculosis.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method effect of GTR with PRF,GTR without PRF, and nomal blood clot on periapical healing 3,6,9,12 months
- Secondary Outcome Measures
Name Time Method effect of early or late periapical healing in between 3 groups and comparison of periapical healing between group 1 and group 2 and also with inter group comparison
Trial Locations
- Locations (1)
Dr Ziauddin ahmed dental college and hospital
🇮🇳Aligarh, UTTAR PRADESH, India
Dr Ziauddin ahmed dental college and hospital🇮🇳Aligarh, UTTAR PRADESH, Indiadisha mahorePrincipal investigator7507741889mahoredisha@gmail.com