comparative assessment of periapical bone healing after endodontic microsurgery using GTR bioabsorbable membrane with and without PRF: A prospective randomized controlled trial

Theprimary goal of endodontic surgery is to eliminate periradicular pathology andaid regeneration of the periapical tissues including the complete healing ofosseous defects. Apico-marginaldefects are localized bony defects that include the entire length of the rooti.e., defect which extends from the periapex tothe alveolar crest to the tooth. This defect caused by combinedperiodontal-endodontic lesion or an endodontic-periodontal lesion. Thetreatment of endodontic-periodontal combined lesions requires both endodontictherapy and periodontal regenerative procedure. Advancement in newer guidedtissue regeneration technique and development of second-generation plateletconcentrate, platelet rich fibrin shows promising result in field of endodonticsurgery. PRF promotes healing of wound, flap stabilization, osseous growth andhemostasis. The present study assess the one-year postoperative healingoutcome of Apico-marginal bone defects treated by endodonticmicrosurgery using two guided regenerative technique. The GTRtechnique compared included placement of a collagen membrane with and withoutthe adjunctive utilization of PRF over the apico-marginal and osseous defectbefore flap closure after performing endodontic microsurgery.