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Oral dexamethasone versus prednisolone in west syndrome

Not Applicable
Completed
Conditions
Health Condition 1: G94- Other disorders of brain in diseases classified elsewhere
Registration Number
CTRI/2021/04/032533
Lead Sponsor
arain Das Vaswani
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
40
Inclusion Criteria

Newly diagnosed children aged 3-36 months with West syndrome

Exclusion Criteria

1. Children with recognized progressive neurological illness

2. Children with renal, pulmonary, cardiac or hepatic dysfunction

3. Children with severe malnutrition as per World Heath Organization criteria

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Primary electroclinical remissionTimepoint: Baseline <br/ ><br>2 weeks
Secondary Outcome Measures
NameTimeMethod
1. Spasm cessation <br/ ><br>2. Greater than 50% reduction in spasm frequency <br/ ><br>3. Greater than 90% reduction in spasm frequency <br/ ><br>4. Resolution of hypsarrhythmiaTimepoint: Baseline <br/ ><br>2 Weeks
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