CTRI/2023/03/050966
Not yet recruiting
未知
EUROIMAGING AND PERIPHERAL BIO MARKERS OF COGNITIVE FUNCTIONING IN UNAFFECTED FIRST DEGREE RELATIVES OF DEMENTIA PROBANDS:AN ENDOPHENOTYPE STUDY
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Health Condition 1: F028- Dementia in other diseases classified elsewhere
- Sponsor
- Central Institute of Psychiatry
- Status
- Not yet recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •INCLUSION CRITERIA (GROUP A)
- •1\.First Degree Relatives of Dementia
- •2\.Family History of Dementia in First degree relatives.
- •3\.First degree relatives of subjects in patient group of either sex.Â
- •4\.Aged between 18\-50 years.
- •5\.No comorbid psychiatric illness,substance use,psychosis,mood disorders.
- •6\.Participants giving written informed consent.
- •7\.Score of 3 or less on General Health Questionnaire 12 (GHQ 12\)
- •INCLUSION CRITERIA (GROUP B) Healthy Controls
- •1\.Score of 3 or less on General Health Questionnaire\-12
Exclusion Criteria
- •EXCLUSION CRITERIA (GROUP A)
- •1\.Underlying Organic disorders, Severe mental illness, substance use disorders, Psychosis, Mood disorders
- •2\.Not giving written informed consent
- •3\.Contraindications for MRI (Metallic Implants)
- •EXCLUSION CRITERIA (GROUP B)
- •1\.Current neurological or any comorbid major psychiatric disorders except nicotine or caffeine dependence.
- •2\.History of substantial brain damage or any neurological procedures.
- •3\.Presence of metallic implants.
- •4\.Score of more than 3 on general health questionnaire GHQ\-12\.
- •EXCLUSION CRITERIA (GROUP C)
Outcomes
Primary Outcomes
Not specified
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