A CLINICAL TRIAL ON AYURVEDIC PANCHAKARMATHEREPY IN EXESSIVE MENSTRUAL FLOW

Phase 2

Not yet recruiting

• Conditions: Excessive and frequent menstruation with irregular cycle. Ayurveda Condition: ASRUGDARAH/RAKTAPRADARAH,

• Registration Number: CTRI/2022/02/039967
• Lead Sponsor: National institute of Ayurveda Jaipur Rajasthan

Brief Summary

Asrigdara is one of the highly prevalent gynecological problems among the females during their reproductive years. Asrigdara or abnormal uterine bleeding is of more concern, because excessive or prolonged bleeding may cause undue disruption of woman’s daily activities & affects woman’s health both physically and psychologically. The incidence rate of Asrigdara is increasing day by day, so if treatment is delayed this can lead to a worsen condition of the patient due to excessive blood loss. Various reports suggest that 30 to 50% of women in the reproductive age group suffer from excessive and irregular uterine bleeding by various causative factors. 28% of the female population consider their menstruation excessive and will plan their social activities around their menstrual cycle, and nearly 10% of employed women will need to take time off from their work because of excessive menstrual loss . 6 % of women aged between 25 to 44 years consult their GPs about excessive menstrual loss every year. Out of them 35 % referred to hospital 60 % will have a Hysterectomy in the next 5 years. Over 75000 hysterectomies are now carried out every year with 30 % of them carried out for menstrual disturbances alone. If Asrigdara is not treated properly, it can cause further bleeding complications like anemia, excessive bleeding can even cause death. . Looking into the pathogenesis of Asrigdara, it occurs due to vitiation of Pitta and Rakta. Due to Apana Vayu Vaigunya with Agnimandya, Rasa Dhatu didn’t formed properly and improper Rasa Dhatu leads to improper Rakta Dhatu formation. In other words, all seven Dhatus formed improperly. Along this, Upadhatu of Rasa i.e. Artava formation is also impaired. Thus, for the treatment of Asrigdara, the drug having the properties of Pittashamana, Vatanulomana, Raktasthapana, Raktasamgrahi, Agnidepana and Garbhashaya Balya etc. are used iii . So the drug which have capacity to break the pathogenesis, arrest the progression of disease, reduce risk of complications and relieve the symptoms should be used in Asrigdara. So there is a great scope of research to find out safe, potent, cost effective procedure from Ayurveda by addressing the root of the problem thereby improving the quality of life of woman. Virechana with trivrilleham because of its pittashodhan property and dashmool taila because of its Tridosha shaman,vatanulomana properties have been taken in the present study to rule out and compare their therapeutic efficacy in the management of asrigdara . Aacharya Bhavmishra has described Kutaki drug as kaphapittapaha, pittarecaka. iv These are the factors why the topic is being selected for the present study.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2022-12-01
• Study Start: 2022-12-02

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Female
• Target Recruitment: 30

Inclusion Criteria

• Patients complaining of Asrigdara having any two of the following symptoms: Heavy menstrual bleeding.
• Prolonged menstrual bleeding.
• Inter menstrual bleeding.
• 2.Hb level equal or more than 8 gm/dl 3.Age between 12 year to 50 years.

Exclusion Criteria

• Pregnant woman 2.
• Patients having bleeding due to abortion.
• Ectopic Pregnancy.
• Patients having any systemic diseases.
• Any type of malignancy.
• Patients having STDs. 9.
• Patients using IUCDs. 10.Thyroid hormones abnormalities 11.Uterine and pelvic pathology like -Polyps, Endometrial T.B, Fibroid, Adenomyosis, PID etc.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Achievement of normal menstruation	8 WEEKS

Secondary Outcome Measures

Name	Time	Method
Improvement in quality of life.

Trial Locations

Locations (1)

National Institute of ayurveda; 🇮🇳 Jaipur, RAJASTHAN, India

National Institute of ayurveda

🇮🇳Jaipur, RAJASTHAN, India

DR Hetal H dave

Principal investigator

9414770823

manjurajalwal@gmail.com