The effect of desmopressin in reducing the incidence of heart transplant surgery complicatio
Phase 1
- Conditions
- transplant cardiac surjery.Surgical operation with transplant of whole organ
- Registration Number
- IRCT2015010512642N8
- Lead Sponsor
- Vice Chancellor for Research and Technological Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
inclusion criteria: age between 20-70 years old; Heart transplant surgery
exclusion criteria: History of previous surgery on chest; Bleeding disorders and hemophilia; Patients with preoperative coagulation tests and platelet be disrupted; Contraindications for use of DDAVP; History of deep vein thrombosis-hematologic disease- carotid plaque due to sever narrowing; Chronic obstructive pulmonary disease
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Chest tube blood volume. Timepoint: During the first 24 hours after surgery. Method of measurement: cc with a calibrated container.;Blood volume required for transfusion. Timepoint: During the first 24 hours after surgery. Method of measurement: Based on the number of units transfused.;FFP volume required for transfusion. Timepoint: During the first 24 hours after surgery. Method of measurement: Based on the number of units injected.
- Secondary Outcome Measures
Name Time Method Thrombin time. Timepoint: before and after transplant surjery. Method of measurement: According to the second with lab kit.;Platelet count. Timepoint: Before and after transplantat surjery. Method of measurement: Based on the number of platelets per ml of blood.