A comparison of different dose intravenous lidocaine for prevent cough and sore throat after awakening from general anesthesia, a double blind randomized control trial
- Conditions
- Sore throat after awakening from general anesthesia.Cough after awakening from general anesthesia,
- Registration Number
- TCTR20200325003
- Lead Sponsor
- Phramongkutklao Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Enrolling by invitation
- Sex
- All
- Target Recruitment
- 184
• agree to receive treatment according to the research plan
• undergoing surgery By choosing the method of anesthesia and endotracheal tube
• Age 18-65 years
• ASA I-II (patients who do not have any underlying disease or have underlying disease that can control the symptoms and do not have severe complications)
• able to read, write and understand Thai
• Refusing to participate in research
• have a history of hypersensitivity to lidocaine or other local anesthetics
• Patients with abnormal liver and kidney function
• Patients with congestive heart failure, recent myocardial infarction and cardiac arrhythmia such as AV block, atria fibrillation, Ventricular tachycardia
• Problems with communication using language (language barrier)
• Patients with a history of asthma or emphysema
• Patients with a history of upper respiratory infections within 2 weeks.
• Patients with high blood pressure and receiving ACEI
• Patients who are pregnant Or is breast-feeding
• The patient undergoes emergency surgery.
• • Patients with adverse effects from coughing, such as patients with increased intracranial pressure and rupture globe
• ASA classification 3 and above
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The effect of intravenous different lidocaine dose that use before extubation about the cough 05/12/2020 four-point scale postoperative room, grade 0 = no coughing, grade 1 = moderate coughing, grade 2 = m
- Secondary Outcome Measures
Name Time Method The effect of intravenous different lidocaine dose that use before extubation about sore throat 05/12/2020 Four-point scale at 1 hr. postoperative, grade 0 no sore throat, grade1 mild, grade2 moderate, grade