Comparing the Combination of Dexmedetomidine and Lidocaine Infusion With Intravenous Lidocaine Infusion in Attenuating heart rate and blood pressure response to Laryngoscopy and Endotracheal Intubation in patients undergoing general anaesthesia.
Not Applicable
- Conditions
- Health Condition 1: - Health Condition 2: O- Medical and Surgical
- Registration Number
- CTRI/2022/11/047632
- Lead Sponsor
- Department of Anaesthesia
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients posted for elective surgeries under general anaesthesia.
Patients of ASA grade I and II
Adult patients(18-60) years
Exclusion Criteria
Hypertensive patients
Previous history of coronary artery disease
History of arrhythmias, pacemakers
Patients allergic to Dexmedetomidine and/or Lidocaine
Usage of beta blockers
Emergency surgeries
Full stomach Patients
Pregnant and Paediatric Patients
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method measurement of Heart rate and Mean Blood PressureTimepoint: Measurement of heart rate and mean blood pressure at following intervals: <br/ ><br>1.Arrival to Operation Theatre. <br/ ><br>2.Two minutes after completion of infusion of the test drug. <br/ ><br>3.Five minutes after completion of infusion of the test drug <br/ ><br>4.Before induction of anaesthesia. <br/ ><br>5.After induction of anaesthesia. <br/ ><br>6.1, 3, 5, 10 minutes after laryngoscopy and endotracheal intubation
- Secondary Outcome Measures
Name Time Method To observe for any adverse effects such as <br/ ><br>bradycardia, hypotension, arrhythmiasTimepoint: intraoperatively