The Efficacy of Tranexamic Acid to Reduce Perioperative Blood Loss and Blood Transfusion in Patients Undergoing Distal Femur Fracture Surgery

Phase 2

Completed

• Conditions: Distal Femur FracturesIntraoperative Blood Loss; Distal Femur Fractures; Blood Loss; Tranexamic Acid

• Registration Number: TCTR20220104001
• Lead Sponsor: Chnburi Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2021-06-30
• Study Start: 2022-01-04
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1. Unilateral distal femur fracture
2. Operative management
3. Age between 20 to 65 years old
4. Closed fracture

Exclusion Criteria

1. Bleeding disorders
2. Serum platelet count less than 150000 per cmm
3. Coagulopathy
4. Venous thrombosis
5. Allergic to Tranexamic Acid
6. Multiple injuries
7. Concomitant vascular injuries
8. Cerebral concussion
9. History of taking anticoagulants
10. Pregnancy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
intraoperative blood loss intraoperative milliliters

Secondary Outcome Measures

Name	Time	Method
VTE 24 hours after surgery By diagnosis