Long Term Outcome Study in Patients With Pituitary Disorders

Active, not recruiting

• Conditions: Pituitary Neoplasms; Pituitary Diseases

• Registration Number: NCT03665064
• Lead Sponsor: University of Alberta

Brief Summary

To determine the outcomes of patients with different pituitary disorders whether they are managed medically, surgically or expectantly.

Detailed Description

A chart audit of around 1500 patients seen in two specific clinics, the Medical Pituitary Clinic and the combined Endocrine/Neurosurgical Pituitary Clinic at the University of Alberta Hospital, will be performed to determine the effectiveness of various treatment strategies on the long term outcome of specific pituitary disorders. The investigator's will collect retrospective demographic (age, sex, ethnicity), clinical (mode of presentation, hormonal parameters) and therapeutic outcome (surgical, medical, expectant and / or radiation treatment; co-morbidities and complications) of patients seen in these two clinics between January 2000 and December 2020.

Basic Information
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Recruitment & Eligibility
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Study & Design

Study Timeline

• Study Start: 2000-01-01
• Study First Submitted: 2018-09-07
• Study First Submitted QC: 2018-09-10
• Study First Posted: 2018-09-11
• Status Verified: 2024-02
• Last Update Submitted: 2024-02-02
• Last Update Posted: 2024-02-05
• Primary Completion: 2024-12-31
• Study Completion: 2024-12-31

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 1500

Inclusion Criteria

• patients with confirmed pituitary disease

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Exclusion Criteria

• patients who do not have confirmed pituitary disease

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Progression free survival after pituitary surgery	up to 17 years post surgery	Using clinical, biochemical and imaging studies of a cohort of surgically operated patients to identify prognostic factors of tumor recurrence