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Detecting endometrial and ovarian cancer with the Pap-smear

Conditions
Endometrial cancerOvarian cancerEndometriumcarcinoomOvariumcarcinoomEierstokkankerBaarmoederslijmvlieskankerPap-smearUitstrijkje
Registration Number
NL-OMON22188
Lead Sponsor
Radboud university medical center
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
150
Inclusion Criteria

Endometrial cancer: all patients presenting with preoperative diagnosis of endometrial cancer (via pipelle endometrial biopsy or dilatation and curettage).

Ovarian cancer: all patients scheduled for surgery for suspected ovarian cancer (RMI>200, ascites).

Exclusion Criteria

Patients who received pelvic radiation in the past and patients with ovarian cancer who do not have a uterus will not be able to participate in this study.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Sensitivity and specificity of the Pap-smear in detecting endometrial and ovarian cancer
Secondary Outcome Measures
NameTimeMethod
The sensitivity and specificity of the cervicovaginal self-sample and the Pipelle endometrial biopsy in detecting endometrial and ovarian cancer.<br /><br>The correlation between DNA alterations in the cervicovaginal self-sample, the Pap-smear and the Pipelle endometrial biopsy and clinicopathologic parameters
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