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Preservation of Fat Free Mass During Weight Loss

Not Applicable
Completed
Conditions
Muscle Loss
Registration Number
NCT03102372
Lead Sponsor
University of Aarhus
Brief Summary

In this study, we aimed to examine the effect of whey protein supplementation given before night sleep on Fat Free Mass (FFM) preservation during a 4 wk period on Very Low Caloric Diet (VLCD).

Half of the participants underwent a 4 week VLCD and walking program, while the other half underwent a 4 week VLCD, walking program and had an additional protein supplement before each night sleep.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
29
Inclusion Criteria
  • Body Mass Index (kg/m^2) > 28
  • Age between 18 and 55 years
Exclusion Criteria
  • Participation in regular resistance-, aerobic- or anaerobic training (>1 h/wk within the last 3 month before intervention start)
  • Diabetes Physical disabilities that would hinder completion of the walking program.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Fat Free MassChange from baseline to after the 4 week intervention period

Dual energy X-ray absorptiometry (DXA)

Secondary Outcome Measures
NameTimeMethod
Oral glucose tolerance testChange from baseline to after the 4 week intervention period

OGTT

Nitrogen balanceChange in nitrogen content from baseline to day 7 and 28 of the intervention period

Three 24 hours urin samples

Fitness levelChange from baseline to after the 4 week intervention period

Bike test

Blood pressureChange from baseline to after the 4 week intervention period

Blood pressure at rest

Fat massChange from baseline to after the 4 week intervention period

DXA

waist circumferenceChange from baseline to after the 4 week intervention period

waist circumference

Performance testChange from baseline to after the 4 week intervention period

Intermittent running test (YY1R1C)

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