The Impact of Neighborhoods, Networks, and Depression on Drug Users' HIV Risk
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 965
- 试验地点
- 2
- 主要终点
- Change from Baseline in Depressive Symptoms Measured by the CESD Scale at 12 months
研究概览
简要总结
The goal of this study is to examine how social networks, neighborhood, and depression are related to HIV risk. The intervention is designed to train individuals to cope with feelings of depression or stress as a way to reduce their risk for HIV.
详细描述
This study included implementation and evaluation of a small group, randomized controlled, phase II intervention to reduce depressive symptoms and HIV risk behaviors among inner city drug users. The intervention included elements of cognitive behavioral therapy (CBT) for depression among impoverished individuals, emphasizing depressive cognitions and behaviors theorized to be associated with depression and with HIV risk behaviors among mildly to moderately depressed drug users. In addition, the study examined active drug users' social and environmental pathways to depression and subsequent HIV risk behaviors. Specifically, we will hypothesized mediating/moderating effects of neighborhood characteristics, social network factors, and individual level factors on depressive symptoms and HIV risk behaviors.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18-55 years old
- •HIV Risk Behavior:
- •3a. Injected drugs more than 3 times in the past week OR
- •3b. Snorted/sniffed heroin or cocaine or smoked crack in the past 6 months AND had 1 of the following sex risks in the past 6 months: i) 2 or more sex partners ii) Had a sex partner who injected drugs iii)Had a sex partner who smoked crack iv) Had a sex partner who was HIV+
- •Willingness to attend group sessions
排除标准
- •Enrolled in another HIV behavioral intervention or depression study in past the 3 years
- •Enrolled in another Lighthouse study in past the 5 years
- •Enrolled in the formative research (Phase 1) or pilot (Phase 2) of the current project.
研究组 & 干预措施
Workshop Control
Participants receive HIV/STDs risk reduction information.
干预措施: Workshop control (Behavioral)
Intervention Workshop
Participants learn skills to cope with depressive symptoms and stress as well as safer sex and injection skills.
干预措施: Workshop (Behavioral)
结局指标
主要结局
Change from Baseline in Depressive Symptoms Measured by the CESD Scale at 12 months
时间窗: 12 months
Change from Baseline in Depressive Symptoms Measured by the CESD Scale at 6 months
时间窗: 6 months
次要结局
- Change from Baseline in Sex Risk Behavior Based on Number of Sex Partners and Condom Use at 12 months(12 months)
- Change from Baseline in Sex Risk Behavior Based on Number of Sex Partners and Condom Use at 6 months(6 months)
- Change from Baseline in Injection Risk Behavior Based on Sharing Needles, Cookers, and Cotton For Injection and Drug Splitting at 6 months(6 months)
- Change from Baseline in Injection Risk Behavior Based on Sharing Needles, Cookers, and Cotton For Injection and Drug Splitting at 12 months(12 months)
研究者
Carl Latkin
Professor
Johns Hopkins Bloomberg School of Public Health