High-intensity Interval Training Training Protocols on Cardiorespiratory Parameters in Patients With Type 2 Diabetes
- Conditions
- Diabetes
- Interventions
- Other: Long durationOther: Short duration
- Registration Number
- NCT03487029
- Lead Sponsor
- Hacettepe University
- Brief Summary
Aim: To assess whether there are different training effects on glucose concentration and cardiorespiratory parameters of different high-intensity training protocols in patients with type 2 diabetes.
Type 2 diabetes is a highly prevalent disease associated with cardiovascular disease leading to high levels of mortality, morbidity and health expenditure, characterized by impaired glucose control during activities and reduced aerobic exercise capacity .
Exercise training is the most effective way to improve compliance, reduce blood glucose concentration and increase insulin sensitivity. Training increases muscle capacity, oxidative capacity and glucose transport, peripheral insulin sensitivity is improved.
Exercise training with high-intensity interval (resting and exercise period) High Intensity Interval Training (HIIT) is a form of exercise training that has recently been widely used in the management of type 2 diabetes, including short duration high intensity exercise periods and lower severity or passive rest periods. There are different HIIT exercise training programs according to physiological responses in the literature. However, long-term and short-term HIIT training training programs were not compared in terms of their effect on glucose concentration and cardiorespiratory fitness. The aim of this study was to compare the effects of different HIIT exercise training programs so that exercise programs for patients with type 2 diabetes could be planned more effectively.
- Detailed Description
This study will be participated patients with Type 2 diabetes. Patients' laboratory values, pulmonary function test, respiratory muscle strength, exercise capacity, physical activity level, quality of life will be evaluated.
Pulmonary function test will be assesed with spirometer, respiratory muscle strength will be evaluated with mouth pressure. Exercise capacity will be evaluated using six minute walking test, incremental shuttle walk test, cycle ergometer. Muscle oxigeneration will be asssed with wearable lactate threshold predicting device. Physical activity level will be evaluated trial accelerometer.
Then, patients will be randomly divided two high intensity interval exercise training groups.
First group: short duration high intensity exercise training (Exercise load phase : 30sn %100 Patients performance, rest phase: 120sn %25 patients performance) Second group: Long duration high intensity interval exercise training (Exercise load phase : 4 dk %100 Patients performance, rest phase: 120sn %25 patients performance) All patients will participate three times a week during eight weeks. The muscle oxigeneration, blood glucose consantration, blood pressure, heart rate will be recorded before and after each exercise session. After 8 week, all test will be done again.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 36
- diagnosis of type 2 diabetes
- aged 18-64 years
- patients can walk and cooperative
- body mass index is less than 40 kg / m2
Individuals have known lung disease,have undergone any cardiac event or surgery within the past six months, have uncontrolled hypertension, and have diabetic complications such as nephropathy, retinopathy and severe neuropathy.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description long duration group Long duration 4dk %85 Wmax 120sn %25 Wmax 3 sessions/week total 8 weeks short duration group Short duration 30sn %100 Wmax 120sn %25 Wmax 3 sessions/week total 8 weeks
- Primary Outcome Measures
Name Time Method muscle oxigeneration Change from baseline muscle oxigeneration at 8 weeks It is evaluate with wearable lactate threshold device on gastrocinemius
- Secondary Outcome Measures
Name Time Method pulmonary parameter-Forced vital capacity before and after 8 weeks Forced vital capacity will be evaluated
pulmonary parameter-Forced vital capacity in the first second before and after 8 weeks Forced vital capacity in the first second will be evaluated
The blood glucose consentration before and after 8 weeks It is evaluate with sample from blood
Functional Exercise capacity before and after 8 weeks İt is evaluated with six minute walk test
Maximal exercise capacity before and after 8 weeks İt is evaluated using with incremental shuttle test
Symptom limited maximal exercise capacity before and after 8 weeks İt is evaluated with cycle ergometer test
Physical activity level before and after 8 weeks ıt is assessed using accelerometer
Lipit profile-High density lipoprotein cholesterol before and after 8 weeks High density lipoprotein cholesterol wiil be assesed
Lipit profile- low density lipoprotein cholesterol before and after 8 weeks low density lipoprotein cholesterol wiil be assesed
Lipit profile- trigliseride before and after 8 weeks trigliseride wiil be assesed
pulmonary parameter-Mid expiratory flow rate before and after 8 weeks Mid expiratory flow rate will be evaluated
Respiratory muscle strength before and after 8 weeks It is evaluated with mouth pressure
pulmonary parameter-Peak expiratory flow before and after 8 weeks Peak expiratory flow will be evaluated
Trial Locations
- Locations (1)
Hacettepe University
🇹🇷Ankara, State, Turkey