Relationship between neuroimaging and clinical course after acute spinal cord injury

• Conditions: S14; S24; Injury of nerves and spinal cord at neck level; Injury of nerves and spinal cord at thorax level

• Registration Number: DRKS00009757
• Lead Sponsor: BG Klinikum Murnau

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2015-12-23
• Study Completion: 2022-04-20
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 63

Inclusion Criteria

Acute paraplegia preoperatively with existing spinal lesion traumatic genesis in the level C5 to Th12. From May 1st 2017 acute paraplegia preoperatively with existing spinal lesion traumatic genesis in the level C5 to C8.

Exclusion Criteria

Age under 18 and over 75 years
Heavy head injury
Multilocular spinal lesions
Cauda equina syndrome
plexus lesion
Peripheral nerve lesion
Pacemaker
Pacemaker leads
Instrumentations with disturbing artifacts generating Cages (eg tantalum)

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Correlation between DTI Parameters (FA, ADC Correlat) an the shifting of ISNCSCI protocol sensory scores (LT, PP) at the time points very acute (day 1-15), acute I (day 16-40), acute II (day 70-98) and chronic (day 300-400).

Secondary Outcome Measures

Name	Time	Method
Correlation between DTI parameters (FA, ADC correlate) and the changes in the protocol with ISNCSCI Total Motor Score, Upper Extremities Motor Score (UEMS), Lower Extremities Motor Score (LEMS), and ASIA Impairment Scale (AIS) at the time points very acute (day 1-15), acute I (day 16-40), acute II (day 70-98) and chronic (day 300-400).