Effects of Exercise in Patients With Coronary Artery Disease Aged 80 Years or Older - a Randomized Controlled Trial

Sahlgrenska University Hospital, Sweden1 site in 1 country34 target enrollmentDecember 2013

ConditionsCoronary Artery Disease

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Coronary Artery Disease
Sponsor: Sahlgrenska University Hospital, Sweden
Enrollment: 34
Locations: 1
Primary Endpoint: Change in maximum aerobic capacity
Status: Completed
Last Updated: 4 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to investigate the effects of exercise for patients with coronary artery disease (CAD) aged 80 years and older, with special reference to maximum aerobic capacity, muscle endurance, physical functioning, level of physical activity, health related quality of life, anxiety, depression and endothelial function, compared to a control group.

Registry

clinicaltrials.gov

Start Date

December 2013

End Date

April 2022

Last Updated

4 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Sahlgrenska University Hospital, Sweden

Responsible Party

Principal Investigator

Maria Bäck

Phd, RPT

Sahlgrenska University Hospital, Sweden

Eligibility Criteria

Inclusion Criteria

•Clinical diagnosis of acute coronary artery disease
•Aged 80 years or older

Exclusion Criteria

•Inability to understand or speak the Swedish language
•Serious physical or psychological disease interfering with participation in an exercise intervention
•Patients are already exercising three times or more/week

Outcomes

Primary Outcomes

Change in maximum aerobic capacity

Time Frame: At baseline and after 4 months

A maximum exercise test on an electronically braked cycle ergometer, with watts as marker of maximum aerobic capacity.

Secondary Outcomes

Change in health related quality of life(At baselline and after 4 months)
Change in anxiety and depression(At baseline and after 4 months)
Change in transthoracic evaluation of resting coronary flow velocity(At baseline and after 4 months)
Change in level of physical activity(At baseline and after 4 months)
Change in endothelial function(At baseline and after 4 months)
Change in muscular endurance(At baseline and after 4 months)
Change in physical functioning(At baseline and after 4 months)