Effect of the Duration of Preoperative Fasting on Hypotension Induced by General Anesthesia in the Elderly Person
Completed
- Conditions
- Preoperative Fasting and Hypotension
- Registration Number
- NCT02891122
- Lead Sponsor
- University Hospital, Brest
- Brief Summary
This study aims to determine if prolonged fasting represents an independent risk factor for hypotension during induction of general anesthesia in the elderly.
- Detailed Description
Preoperative fasting aims to reduce the risk of adverse events (eg, inhalation), but may be responsible for dehydration whose consequence is a major hypotension. This problem of hypotension is important because it (MAP \<55 mmHg) is directly correlated to the occurrence of pejorative events on the cardiac and renal level and even more so that the duration of the hypotension is long.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 56
Inclusion Criteria
-
Risk Score anesthetic ASA I-III
-
Patients ≥ 70 years
-
Suffering from a femoral neck fracture to be treated surgically:
- either through prosthesis,
- either by intramedullary nailing (gamma nail)
Exclusion Criteria
- Risk Score anesthetic ASA IV
- Patient on Angiotensin Converting Enzyme (ACE) inhibitors or ARBs (ARA2) within 10 hours before surgery
- Obesity (BMI> 35) or weight <40kg
- Need to make a rapid sequence induction
- Inability to achieve the femoral block (standardization of induction) or patient refusal with respect to the technique.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Follow-up of the variation of the Mean arterial pressure 8 months
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
CHRU de Brest
🇫🇷Brest, France