Post intubation hemodynamic effects of intravenous lidocaine in patients with severe brain trauma

Phase 2

• Conditions: Patients with severe head trauma.; Intracranial injury

• Registration Number: IRCT2013042813150N1
• Lead Sponsor: Vice-chancellor for research, Tabriz University of Medical Sciences, Faculty of Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

all patients aged 65-18 years with traumatic brain injury with GCS <9; patients who have been intubated prior to admission to the emergency room; before referring patients to the emergency room, and inotropic drugs have not received isotonic fluids. Exclusion criteria: patients aged 18 years and above 65 year; patients with heart failure; in patients with shock, hypovolemia, sepsis and cardiogenic reason; patients with a previous history of heart disease and hypertension; start inotropic drugs before intubation and evidence of cardiac arrhythmia.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Heart Rate. Timepoint: Once before and once after intubation. Method of measurement: by an automatic blood pressure cuff.;Systolic Arterial pressure. Timepoint: Once before and once after intubation. Method of measurement: by an automatic blood pressure cuff.;Diastolic arterial pressure. Timepoint: Once before and once after intubation. Method of measurement: by an automatic blood pressure cuff.;Mean arterial pressure. Timepoint: Once before and once after intubation. Method of measurement: by an automatic blood pressure cuff.

Secondary Outcome Measures

Name	Time	Method
The rate of use of isotonic fluids. Timepoint: After intubation. Method of measurement: Chart of Fluids.;The rate of use of inotropic agents. Timepoint: After intubation. Method of measurement: Chart of drugs.