albuphine as an addition to Bupivacaine in Supraclavicular block for Upper Limb Orthopedic Surgeries.
Phase 4
- Conditions
- Health Condition 1: null- patients posted for upper limb orthopaedic surgery of 18 to 60 yrs of age belonging to ASA I and II
- Registration Number
- CTRI/2017/07/009057
- Lead Sponsor
- Department of Anaesthesiology And Sir Takhatsinhji Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
Informed written consent for participation in study.
Gender: Either gender.
Patients scheduled for elective upper limb orthopedic surgery
ASA physical status I and II.
BMI <= 25kg/m2.
Exclusion Criteria
1.Patients refusing consent.
2.Contraindications to regional anesthesia:
Previous nerve injury.
History of drug dependence/abuse.
History of drug allergy.
Allergic to local anaesthetics.
Patients taking analgesics and sedatives.
Patients on anticoagulants.
History of bleeding disorders.
Psychiatric illness.
Uncooperative patients.
3.Any major systemic illness like hypertension, heart block etc.
4.Antenatal females and lactating mother.
5.Inadequate effect requiring supplementation.
6.ASA physical status III and above.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Onset, peak and duration <br/ ><br>of sensory blockade. <br/ ><br>2.Onset, peak and duration <br/ ><br>of motor blockade. <br/ ><br>3.Duration of effective <br/ ><br>post-operative analgesia. <br/ ><br>4.Total dose and frequency <br/ ><br>of rescue analgesics <br/ ><br>required in 24 hours. <br/ ><br>5.Ramsey Sedation score.Timepoint: baseline and than 1 min,3 min,5 min,10 min,15 <br/ ><br>min,30 min, 1 hour,2 hour, 3 hour, 4 hour and <br/ ><br>every 2 hourly till 24 hours after brachial block <br/ ><br>Secondary
- Secondary Outcome Measures
Name Time Method 1.Effects on hemodynamic <br/ ><br>variables Heart Rate, <br/ ><br>Mean Arterial Blood andperipheral oxygen <br/ ><br>saturation.Timepoint: baseline and than 1 min,3 min,5 min,10 min,15 <br/ ><br>min,30 min, 1 hour,2 hour, 3 hour, 4 hour and <br/ ><br>every 2 hourly till 24 hours after brachial block