Comparison of the effect of ketamine and pethidine on pain control

Phase 3

• Conditions: Condition 1: Fracture of upper limb. Condition 2: Fracture of lower limb.; Fracture of upper limb, level unspecified; Fracture of lower leg, including ankle

• Registration Number: IRCT20230228057570N1
• Lead Sponsor: Ilam University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 25 July 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

candidate for elective orthopedic surgery with general anesthesia and class l and ll in the ASA classification
Age range from 18 to 60 years
No history of opioid addiction
Absence of underlying diseases such as: liver and kidney failure, history of seizures, pregnancy and breastfeeding, high ICP (intracranial pressure) and glaucoma, thyrotoxicosis, high blood pressure, diabetes, heart disease and history of disease respiratory
No history of disorders such as mental retardation or psychological illness
No history of drug sensitivity to pethidine or ketamine
No history of chronic use of painkillers

Exclusion Criteria

opioid addiction
underlying diseases such as: liver and kidney failure, history of seizures, pregnancy and breastfeeding, high ICP (intracranial pressure) and glaucoma, thyrotoxicosis, high blood pressure, diabetes, heart disease and history of disease respiratory
mental retardation or psychological illness
drug sensitivity to pethidine or ketamine
chronic use of painkillers

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain score based on Visual Analogue Scale tool. Timepoint: at recovery room, 6 and 12 hours after surgery. Method of measurement: Visual Analogue Scale tools.