Targeted-Volume Non-Invasive Ventilation in Post Planned Extubation in Medical Intensive Care Unit Patients
Phase 3
Completed
- Conditions
- Acute respiratory failureReintubation rateMortality rateAcute respiratory failureReintubation rateTargetted volume non invasive ventilation
- Registration Number
- TCTR20160310001
- Lead Sponsor
- Chulalongkorn university
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 58
Inclusion Criteria
Intubation due to Acute respiratory failure (PaO2 < 60mmHg or SpO2<90% , PaCO2 > 50 mmHg with pH <7.30)
Mechanical ventilation longer than 48 hours
Readiness to extubation
No history of extubation failure (in this admission)
No facial anomaly, No unable to fit mask
Informed consent
Exclusion Criteria
Post tracheostomy
Patient with upper airway obstruction immediate after extubation (develop inspiratory stridor)
Cause of respiratory failure from COPD with acute exacerbation or cardiogenic pulmonary edema
Claustrophobia
Patient incooperative
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reintubation rate 48 hours after extubation incidence rate
- Secondary Outcome Measures
Name Time Method mortality rate, incidence of pneumonia 28 days after extubation Incidence rate