Kardiale Innervation bei genetischen Arrhythmiemodellen in Menschund Maus
- Conditions
- The longQT-syndrome is a genetically detemined malfunction of ion channels. The identified genes in longQT-patients encode cardiac ion channels or accessory proteins affecting the function of different ion channels. A certain gene defect can be associated with different symptoms regarding to the severity of the disease. Additionally, an increased sympathetic tone is a major trigger for potentially life threatening tachyarrhythmias depending on the genetical subtype.
- Registration Number
- EUCTR2006-002767-41-DE
- Lead Sponsor
- Sonderforschungsbereich 656 (SFB 656)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
100 patients with longQT syndrome and 40 healthy control subjects (male and female, >18 years) will be enrolled in the study
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
- pregnant or breastfeeding women (confirmed by pregnancy test before scanning)
- patients and volunteers younger thyn 18 years
- patients who are kept in a mental institution upon official directive
- patients who already took part in another resaerch project
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method