Role of zinc supplementation in promoting recovery from acute bronchiolitis (a viral respiratory tract infection) in children.
Phase 4
Completed
- Conditions
- Health Condition 1: J219- Acute bronchiolitis, unspecifiedHealth Condition 2: null- Bronchiolitis
- Registration Number
- CTRI/2011/07/001864
- Lead Sponsor
- niversity College of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
Children (between 3 months to 2 years) with a clinical diagnosis of severe bronchiolitis (inability to feed, severe distress,apnea, hypoxemia, lethargy or cyanosis)
Exclusion Criteria
1)They were receiving or had received any micronutrient supplementation within last 4 weeks prior to onset of present illness.
2)Clinical evidence of underlying cardiac or chronic pulmonary disease
3)There is a co-morbid condition (severe malnutrition, meningitis) present at the time of admission.
4)There is lobar consolidation in chest x-ray.
5)Intubation/ventilation is required before enrolment.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Resolution of severe bronchiolitis (when lower chest retraction and the danger signs are no longer present) <br/ ><br>2. Time to resolution of lower chest indrawing, fast breathing, inability to feed <br/ ><br> <br/ ><br>Timepoint: 7 days
- Secondary Outcome Measures
Name Time Method 1. Recovery rate (proportion of children with resolution of severe bronchiolitis) <br/ ><br>2. Duration of oxygen therapy <br/ ><br>3. Duration of IV fluids <br/ ><br>4. Duration of hospitalization <br/ ><br>Timepoint: 7 days