Echocardiographic Assessment of the Right Ventricle in Healthy Subjects During Stress Test in the Mexican Population
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Response of diastolic and systolic function of the right ventricle during stress test by echocardiography in a healthy Mexican Cohort
研究概览
简要总结
The echocardiographic indices of the right ventricle function vary significantly with demographic and anthropometric of each population factors and are associated with poor prognosis in several cardiovascular diseases.
This study aims to investigate exercise-induced changes in echocardiographic indices of the right ventricle function in healthy volunteers and establish the reference values to the Mexican population.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy men or women
- •Age ≥18 years and <
- •No history or symptoms of cardiovascular or lung disease
- •No cardiovascular risk factors, that is, arterial systemic hypertension, smoking, diabetes, dyslipidemia
- •No ongoing or previous cardio or vasoactive treatment
- •Normal ECG
- •Normal physical examination
- •Able to use the semi-supine exercise bicycle
- •Able to give informed consent
排除标准
- •Tricuspid regurgitation more than mild
- •Poor acoustic window.
- •Professional sports activity
- •Pregnancy
- •Obesity (body mass index [BMI], ≥30 kg/m2).
- •No knowledge of serum lipid or glucose levels at any time
- •Inability to provide consent
结局指标
主要结局
Response of diastolic and systolic function of the right ventricle during stress test by echocardiography in a healthy Mexican Cohort
时间窗: 1 hour
The following variants will be measured by echocardiography during rest and peak exercise Left atrium (LA) * LA volume index Left ventricle (LV) * LV telediastolic diameter * LV telesystolic diameter * LV posterior wall Right atrium (RA) * RA area Right ventricle (RV) * RV basal dimensión * RV mid cavity dimension; * RV longitudinal dimension * Distal, RV outflow tract dimension at the distal or pulmonic valve level * Proximal RV outflow tract dimension at the proximal subvalvular level * Tricuspid annular plane systolic excursion * RV free Wall strain * Inferior cava vein PW Doppler * E wave mitral * A wave mitral * E wave /A wave mitral * E-wave at mitral annulus (cm/s) * E-wave at mitral annulus / A-wave at the mitral annulus * E wave/ E-wave at the mitral annulus * E tricuspid (E) * A tricuspid (A) * E/A * E-wave at the tricuspid annulus * Systolic pulmonary artery pressure * Mean pulmonary artery pressure * Stroke volume * Cardiac output
次要结局
未报告次要终点
研究者
Miguel Ayala León
cardiovascular critical care unit director
Hospital Beneficencia Espanola de Puebla