Echocardiographic Assessment of the Right Ventricle in Healthy Subjects During Stress Test in the Mexican Population
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Echocardiography, Stress
- Sponsor
- Miguel Ayala León
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Response of diastolic and systolic function of the right ventricle during stress test by echocardiography in a healthy Mexican Cohort
- Last Updated
- 5 years ago
Overview
Brief Summary
The echocardiographic indices of the right ventricle function vary significantly with demographic and anthropometric of each population factors and are associated with poor prognosis in several cardiovascular diseases.
This study aims to investigate exercise-induced changes in echocardiographic indices of the right ventricle function in healthy volunteers and establish the reference values to the Mexican population.
Investigators
Miguel Ayala León
cardiovascular critical care unit director
Hospital Beneficencia Espanola de Puebla
Eligibility Criteria
Inclusion Criteria
- •Healthy men or women
- •Age ≥18 years and \<
- •No history or symptoms of cardiovascular or lung disease
- •No cardiovascular risk factors, that is, arterial systemic hypertension, smoking, diabetes, dyslipidemia
- •No ongoing or previous cardio or vasoactive treatment
- •Normal ECG
- •Normal physical examination
- •Able to use the semi-supine exercise bicycle
- •Able to give informed consent
Exclusion Criteria
- •Tricuspid regurgitation more than mild
- •Poor acoustic window.
- •Professional sports activity
- •Pregnancy
- •Obesity (body mass index \[BMI\], ≥30 kg/m2).
- •No knowledge of serum lipid or glucose levels at any time
- •Inability to provide consent
Outcomes
Primary Outcomes
Response of diastolic and systolic function of the right ventricle during stress test by echocardiography in a healthy Mexican Cohort
Time Frame: 1 hour
The following variants will be measured by echocardiography during rest and peak exercise Left atrium (LA) * LA volume index Left ventricle (LV) * LV telediastolic diameter * LV telesystolic diameter * LV posterior wall Right atrium (RA) * RA area Right ventricle (RV) * RV basal dimensión * RV mid cavity dimension; * RV longitudinal dimension * Distal, RV outflow tract dimension at the distal or pulmonic valve level * Proximal RV outflow tract dimension at the proximal subvalvular level * Tricuspid annular plane systolic excursion * RV free Wall strain * Inferior cava vein PW Doppler * E wave mitral * A wave mitral * E wave /A wave mitral * E-wave at mitral annulus (cm/s) * E-wave at mitral annulus / A-wave at the mitral annulus * E wave/ E-wave at the mitral annulus * E tricuspid (E) * A tricuspid (A) * E/A * E-wave at the tricuspid annulus * Systolic pulmonary artery pressure * Mean pulmonary artery pressure * Stroke volume * Cardiac output