Efficacy of Tranexamic Acid for Dental Extractions in patients with Inherited Bleeding Disorders

Phase 3

• Conditions: von Willebrand's Disease; Hereditary factor VIII deficiency; Hereditary factor IX deficiency; Oral Hemorrhage.; D68.0; C07.465.625

• Registration Number: RBR-2jx9r5
• Lead Sponsor: Centro de Hematologia e Hemoterapia - HEMOCENTRO

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-01-29
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Data analysis completed
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Adult patients (over 18 yrs old); Patients with inherited bleeding disorders; Male and females; Patients in follow up at Hemocentro de Campinas/UNICAMP and/or at Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (HCFMRP-USP); Patients who need at least one tooth to be removed;

Exclusion Criteria

Patients who disagree with the terms of the informed consent; Patients who are incapable to give your own consent due to psychiatric and/or mental reasons; Under age patients (less than 18 yrs old); Pregnant women and/or breastfeeding women; Edentulous patients;
6- Hemophilic patients with inhibitors against coagulation plasmatic factors; Patients with high risk for thrombosis, or with a previous thromboembolic event; Patients who had a previous hypersensibility reaction related to tranexamic acid use; Patients who have used acetylsalicylic acid, or non-steroidal anti-inflammatory drugs up to two weeks before the dental extraction.

Study & Design

• Study Type: Intervention
• Study Design: Not specified