Platelet-rich plasma injections and periodontal health

Not Applicable

Completed

• Conditions: Anterior teeth crowding; Oral Health

• Registration Number: ISRCTN18306557
• Lead Sponsor: Tishreen University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2023-08-23
• Study Start: 2024-08-30
• Last Update Posted: 9 September 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1. Individuals aged 18 to 25 years with anterior teeth crowding ranging from 3 to 6 mm
2. Maintaining excellent oral hygiene and periodontal health
3. Without prior orthodontic treatment history

Exclusion Criteria

1. Systemic medical conditions
2. Dental anomalies in tooth size or shape
3. Current use of anti-inflammatory medications

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Salivary aspartate aminotransferase (AST) activity measured using a spectrophotometer at baseline (before treatment), 1 hour after the start of treatment, 1 week after, and 2 weeks after treatment

Secondary Outcome Measures

Name	Time	Method
Periodontal health parameters, including Periodontal Pocket Depth (PPD), Clinical Attachment Level (CAL), Bleeding on Probing (BOP), and Gingival Recession (GR), were recorded using a UNC-15 periodontal probe at baseline, 4 weeks, 8 weeks, and 12 weeks.