The Effect of tranexamic acid on the volume of bleeding during and after elective cesarean section in moderate and high risk patients
- Conditions
- Obstetrics and Gynecology diseases.Encounter for care and examination of mother immediately after deliveryZ39.0
- Registration Number
- IRCT20211114053061N1
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 200
Term pregnant mothers who are candidates for elective caesarean section have medium and high risk for postpartum bleeding
Patients with history of postpartum hemorrhage in the past, presence of placenta previa, history of myomectomy, previous uterine surgery, multiple laparotomy, history of previous caesarean section more than 3 times, platelet count less than 75000, anemia with hemoglobin less than 10, polyhydramnios, macrosomia Weight more than 4000 grams, multiples, BMI more than 30, severe pregnancy complications such as preeclampsia
Unwillingness of patients to participate in the study and their infection with Corona
Hypersensitivity to tranexamic acid
VT Score more equal to 3
Underlying medical disease, placenta provia and placental adhesion disorders such as accreta and percreta, active bleeding and placental abruption, caesarean section with midline incision, drugs affecting tranexamic acid
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Bleeding volume. Timepoint: During surgery and 6 hours after surgery. Method of measurement: Collecting the amount of gas and liquid and bottle suction.;Hematocrit level. Timepoint: During surgery and 6 hours after surgery. Method of measurement: laboratory.
- Secondary Outcome Measures
Name Time Method Blood transfusion. Timepoint: After surgery. Method of measurement: Questionnaire.