Coagulation effect of four common plasma volume expanders
- Conditions
- Fluid/Plasma substitution during total hip replacement
- Registration Number
- EUCTR2007-000729-24-SE
- Lead Sponsor
- niversity Hospital Linköping
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
Consecutive patients scheduled for total hip relacement
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
Alergic reactions to any of the IMP´s, diabetes and major cardiopulmonary disease
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Main Objective: Study influence of four common volume expanders on operative and postoperative bleeding and on coagulation (InTEG)(clot formation).<br>;Secondary Objective: influence on other coagulation tests depending on volume expander chosen;Primary end point(s): Endpoint after 80 patients (20 in each study group)<br><br>Evaluation of the bleeding, coagulation factors and measurements taken.<br>Hemoglobine, albumine, InTEG, Thrombine complex, Anti-thrombine complex, <br>D-dimer, Soluble P-selectine, v Willibrand factor.<br><br><br>
- Secondary Outcome Measures
Name Time Method