A Randomized Controlled Study of the Effect of Intratracheal and Intravenous Lignocaine on Airway and Hemodynamic responses in comparison with placebo Control during Emergence and Extubation in Laparoscopic Cholecystectomy under General Anesthesia at SMS Medical College, Jaipur
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 156
- 试验地点
- 1
- 主要终点
- 1.Proportion of cases of each cough reflex grade.
研究概览
简要总结
This is a prospective interventional double blind study to compare how Lignocaine and it’s different routes of administration influence the stability of the selected patients airway and hemodynamic status during critical period when patients regain consciousness and have breathing tube removed after surgery under general anaesthesia.This type of study is valuable for improving perioperative care and managing potential complications during the recovery phase after surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Patients undergoing laparoscopic cholecystectomy under general anaesthesia.
- •2.Patients giving written and informed consent.
- •3.Patients age group between 18-70 years.
- •4.Patients with an American Society of Anaesthesiologist (ASA)class1,2&3.
排除标准
- •1.Patients with previous history of anaphylaxis/known allergy to lignocaine.
- •2.Patients with high risk of aspiration.
- •3.Patients with anticipated difficult airway.
- •4.Patients with history of chronic cough or bronchial asthma.
- •5.Patients with history of hypertension on beta blockers.
- •7.Patient already a part of any other study.
结局指标
主要结局
1.Proportion of cases of each cough reflex grade.
时间窗: Monitoring parameters at baseline , extubation, 1,2,3 and 5 minutes before and after extubation.
2.Mean of Heart rate , Systolic blood pressure, Diastolic blood pressure.
时间窗: Monitoring parameters at baseline , extubation, 1,2,3 and 5 minutes before and after extubation.
次要结局
- 1.Mean emergence time(2.Proportion of cases with adverse events)
研究者
Dr Anupama Gupta
SMS Medical College