Comparison of PRS According to Inhalation Agent During LDLT

Phase 4

Completed

• Conditions: Liver Transplantation; Postreperfusion Syndrome
• Interventions: Drug: Desflurane; Drug: sevoflurane

• Registration Number: NCT01886664
• Lead Sponsor: Seoul National University Hospital

Brief Summary

The investigators tried to evaluate the effect of desflurane on the incidence of postreperfusion syndrome during living donor liver transplantation surgery. The investigators used sevoflurane as a comparison.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2012-08-20
• Study Start: 2012-12
• Study First Submitted QC: 2013-06-21
• Study First Posted: 2013-06-26
• Primary Completion: 2013-11
• Study Completion: 2013-12
• Status Verified: 2014-06
• Last Update Submitted: 2014-06-25
• Last Update Posted: 2014-06-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

• elective LDLT

Exclusion Criteria

• age < 18, age > 65
• patient refusal
• re-transplantation

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Desflurane	Desflurane	Performing liver transplantation under general anesthesia using desflurane
Sevoflurane	sevoflurane	Performing liver transplantation under general anesthesia using sevoflurane

Primary Outcome Measures

Name	Time	Method
frequency of PRS	immediately after reperfusion	reperfusion syndrome occurs, if it occurs, immediately after reperfusion. Therefore, the primary outcome, reperfusion syndrome, can only be assessed immediately after reperfusion.

Secondary Outcome Measures

Name	Time	Method
ICU length of stay	after LT until the patient is transferred to the ward

Trial Locations

Locations (1)

Seoul National University Hospital; 🇰🇷 Seoul, Korea, Republic of