– HealthFit – The effects of high-intensity interval training versus an active control group on depressive symptoms and their concurrent biomarkers in outpatients diagnosed with Major Depressive Disorder - – HealthFit –

Deutsche Sporthochschule Köln0 sites44 target enrollmentMay 2, 2023

Overview

No summary available.

Registry

who.int

Start Date

May 2, 2023

End Date

TBD

Last Updated

last year

Study Type

Interventional

Sex

All

Sponsor

•Participants must be native German speakers diagnosed with major depressive disorder by certified clinicians and be outpatients.
•To be recognised as suffering from Major Depressive Disorder (from mild to moderate), participants need to state at least five and a maximum of seven of nine symptoms of the DSM\-5 depression definition nearly every day for at least two weeks.
•Medication: None or stable for at least two weeks before inclusion. If benzodiazepine or benzodiazepine\-like medication: last intake maximum 24h before the beginning of the study. Assessment of the level of anti\-depressive medication in the peripheral blood at inclusion and after completion of the study

•\- Physical exercise: Engaged in \>2 h per week.
•\- Body Mass Index: \<18 and \> 30 kg/m2
•\- Comorbid diseases: Metabolic, hormonal, renal, intestinal, neuroendocrine diseases, chronic infection, drug addiction, or other diagnosed psychiatric disorders (e.g., bipolar disorder, personality disorder, psychosis)
•\- Smoking: \>20 cigarettes per day in the past three months
•\- Alcohol use: AUDIT sum score \>19
•\- Supplement: tryptophan\-related supplements
•\- Others: Pregnancy, Breastfeeding, Night\-work shift