Skin Sympathetic Nerve Activity and Cardiac Arrhythmia

Not Applicable

Completed

• Conditions: Sudden Death; Ventricular Tachycardia; Persistent Atrial Fibrillation
• Interventions: Device: SKNA recording

• Registration Number: NCT04918303
• Lead Sponsor: University Hospital, Bordeaux

Brief Summary

Sympathetic tone is important in cardiac arrhythmogenesis. The simultaneous recording of sympathetic nerve activity (SNA) and electrocardiogram (ECG) was obtained by invasive method. The purpose of this protocol is to further develop this recording method to turn it into a new non-invasive tool for arrhythmia prediction and detection. This method may also be useful in validating the results of surgical procedures aimed at sympathetic denervation

Detailed Description

Not available

Study Timeline

• Study Start: 2021-05-03
• Study First Submitted: 2021-06-02
• Study First Submitted QC: 2021-06-02
• Study First Posted: 2021-06-08
• Primary Completion: 2023-10-12
• Study Completion: 2023-10-12
• Status Verified: 2024-05
• Last Update Submitted: 2024-05-16
• Last Update Posted: 2024-05-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• patient hospitalized at Bordeaux University Hospital for sudden death, ventricular tachycardia, persistent or paroxysmal atrial fibrillation treated by ablation and/or vein of Marshall ethanol infusion

Exclusion Criteria

• pregnancy,
• patient under 18 year old,
• patient with a cardiac stimulation device

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
SKNA group	SKNA recording	-

Primary Outcome Measures

Name	Time	Method
Delay between the discharge of the sympathetic system and the rhythmic event.	Month 6	Temporal correlation of occurrence of sympathetic electrical event and cardiac arrhythmia by the MacNemar test will be performed.

Trial Locations

Locations (1)

Bordeaux University Hospital; 🇫🇷 Pessac, France