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Clinical Trials/PACTR202301861240705
PACTR202301861240705
Not yet recruiting
未知

A prospective clinical and radiological study of incidental cerebral small vessel disease: Aspirin versus Cilostazol (PACCS)

Hany Aref0 sites220 target enrollmentDecember 21, 2021
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ConditionsNervous System Diseases

Overview

Phase
未知
Intervention
Not specified
Conditions
Nervous System Diseases
Sponsor
Hany Aref
Enrollment
220
Status
Not yet recruiting
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
December 21, 2021
End Date
TBD
Last Updated
2 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
Hany Aref

Eligibility Criteria

Inclusion Criteria

  • •Patient aged 45 or Above suffering from incidental cerebral SVD
  • •Patients presenting with slowly progressive cognitive, urinary, gait abnormalities and/or depression, rather than acute stroke presentation.
  • •MRI brain suggestive of small vessel disease in the form of deep white matter hyperintensities (WMH), lacunes, cerebral microbleeds, enlarged Virchow spaces, silent small subcortical infarct

Exclusion Criteria

  • •? Patients with acute onset stroke of any source (Ex: CADASIL)
  • •? Patients with past history of acute large vessel stroke
  • •? Patients with large vessel occlusion or stenosis \>50%
  • •? Contraindication to MRI (as pacemakers or metal plates and screws)
  • •? Alcohol addiction or substance abuse (to exclude substance induced vasculitis)
  • •? Any neurological disease affecting white matter (eg; Multiple sclerosis, sarcoidosis, etc),
  • •? Any neurological disease presenting with symptoms similar to cerebral small vessel disease

Outcomes

Primary Outcomes

Not specified

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