A prospective clinical and radiological study of incidental cerebral small vessel disease: Aspirin versus Cilostazol (PACCS)

Hany Aref0 个研究点目标入组 220 人开始时间: 2021年12月21日最近更新: 2023年5月29日

适应症

试验速览

暂无简介。

•Patient aged 45 or Above suffering from incidental cerebral SVD
•Patients presenting with slowly progressive cognitive, urinary, gait abnormalities and/or depression, rather than acute stroke presentation.
•MRI brain suggestive of small vessel disease in the form of deep white matter hyperintensities (WMH), lacunes, cerebral microbleeds, enlarged Virchow spaces, silent small subcortical infarct

•? Patients with acute onset stroke of any source (Ex: CADASIL)
•? Patients with past history of acute large vessel stroke
•? Patients with large vessel occlusion or stenosis >50%
•? Contraindication to MRI (as pacemakers or metal plates and screws)
•? Alcohol addiction or substance abuse (to exclude substance induced vasculitis)
•? Any neurological disease affecting white matter (eg; Multiple sclerosis, sarcoidosis, etc),
•? Any neurological disease presenting with symptoms similar to cerebral small vessel disease

发起方

Hany Aref