MedPath

Comparison of the Analgesic Efficacy of Ultrasound-guided Serratus Anterior Plane Block and Serratus Posterior Superior Intercostal Plane Block for Breast Surgery: a Randomized Controlled Trial

Not Applicable
Completed
Conditions
Analgesia
Interventions
Registration Number
NCT06436599
Lead Sponsor
Mustafa Burgac
Brief Summary

The application of regional anaesthetic procedures in breast surgery is associated with a lower incidence of chronic pain, reduced morbidity, shorter hospital stay and less opioid requirement. Therefore, we aimed to compared the postoperative analgesic efficacy of Serratus Anterior Plan Block and Serratus Posterior Superior Intercostal Plan Block in breast surgery.

Detailed Description

Breast surgery is one of the most common operations performed by General Surgery and may be associated with acute postoperative pain. Acute postoperative pain is an independent risk factor for the development of chronic pain after mastectomy. Various regional anaesthetic procedures have been tried to achieve better acute pain control and thus less chronic pain. The use of regional anaesthetic procedures in breast surgery is associated with a lower incidence of chronic pain, reduced morbidity, shorter hospital stay and less opioid requirement.

Interfascial plane blocks have become popular because they are easy to perform and safe. Since interfascial plan blocks are based on the injection of local anaesthetic between two fasciae, the complication rate such as nerve damage is very low. With this method, effective analgesia can be provided in various areas such as abdominal, thoracic and lumbar regions while reducing opioid consumption and avoiding neuraxial methods.

In randomised controlled trials investigating the efficacy of Serratus Anterior Plane Block for postoperative analgesia management after breast surgery, adequate analgesia was reported.

Serratus posterior superior intercostal plan block, a newly defined interfascial plan block, has been shown to provide a wide sensory blockade between intercostal muscles. Postoperative analgesic efficacy has been demonstrated in thoracic, breast and shoulder surgeries.

The aim of our study was to compared the postoperative analgesic efficacy of Serratus Anterior Plan Block and Serratus Posterior Superior Intercostal Plan Block in breast surgery.

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
62
Inclusion Criteria
  • unilateral mastectomy(modified radial mastectomy)
  • ASA I-III risk group
Exclusion Criteria
  • Coagulopathy
  • Wound and infection in the block area
  • Local anaesthetic allergy
  • Mental retardation
  • Non-cooperative
  • Pregnant patients

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Patients with serratus posterior superior intercostal plan blockplane block with %0.25 30 ml bupivacaineSerratus posterior superior intercostal plane block was applied to a certain group of patients for postoperative anaesthesia.
Patients with serratus anterior plan blockplane block with %0.25 30 ml bupivacaineSerratus anterior plane block was applied to a certain group of patients for postoperative anaesthesia.
Primary Outcome Measures
NameTimeMethod
Comparison of tramadol(mg) consumptionwithin 24 hours postoperative

Using a patient-controlled analgesia device, tramadol consumption and total tramadol consumption will be compared between 0-1st hour, 1st-4th hour, 4th-8th hour, 8th-12th hour, 12th-24th hour postoperatively.

Secondary Outcome Measures
NameTimeMethod
Evaluation of analgesic efficacy of postoperative plan blocks with numerical pain scorewithin 24 hours postoperative

Evaluation of which of the two plan blocks is more effective in postoperative analgesia.

Postoperative pain scores will be evaluated with a numerical pain score. Evaluation will be performed postoperatively at 30. minutes, 1. hour, 4. hours, 8. hours, 12. hours and 24. hours. A lower numeric pain scale indicates a lower level of pain.

perioperative remifentanil consumptionperioperative

The amounts (mcg) of remifantanil consumed during the surgical procedure will be compared

rescue anesthesiawithin 24 hours postoperative

In the postoperative 24-hour period, tenoxicam will be administered and recorded as rescue analgesia to patients who feel pain despite patient-controlled nalgesia (tramadol).

postoperative nausea-vomiting (PONV)within 24 hours postoperative

The number of times of nausea and vomiting in the postoperative period will be recorded and compared in both patient groups. A lower numerical value of postoperative nausea-vomiting indicates better patient comfort in the postoperative period.

surgeon and patient satisfaction (5-point Likert scale)24 hours after surgery

At postoperative discharge, 5-point Likert satisfaction questionnaire will be administered to the surgeon and the patient. A high numerical value on a five-point Likert satisfaction scale indicates that the surgeon and the patient are satisfied with the procedure performed.

Trial Locations

Locations (1)

Istanbul Professor Doctor Süleyman Yalçın City Hospital

🇹🇷

İstanbul, Turkey

© Copyright 2025. All Rights Reserved by MedPath