Comparison study on the effect of prenatal administation of high dose and low dose folic acid on surem RANKL/OPG ratio in pregnancy
Phase 3
- Conditions
- pregnant women.Eclampsia
- Registration Number
- IRCT2013122315903N1
- Lead Sponsor
- Drug Applied Research Center, Tabriz University of Medical Sciences- Tabriz- iran
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 88
Inclusion Criteria
Inclusion Criteria: Pregnant women with mean of 30-20 years
Exclusion Criteria
Hstory of heart disease; chronic hypertension;diabetes mellitus;renal disease; collagen tissue disease; history of preterm labor; abortion; taking calcium and ferrous sulfate; liver disease
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Osteoprotegerin. Timepoint: Before intervention and 36th week of pregnancy. Method of measurement: ELISA Kit.;RANKL. Timepoint: Before intervention and 36th week of pregnancy. Method of measurement: ELISA Kit.;TNFa. Timepoint: Before intervention and 36th week of pregnancy. Method of measurement: ELISA Kit.
- Secondary Outcome Measures
Name Time Method Calcium. Timepoint: Before intervention and 36th week of pregnancy. Method of measurement: auto analyzer& Compared with control.;Phosphorus. Timepoint: Before intervention and 36th week of pregnancy. Method of measurement: auto analyzer& Compared with control.;Alkaline phosphatase. Timepoint: Before intervention and 36th week of pregnancy. Method of measurement: auto analyzer& Compared with control.